15
Aug
2021
Lidocaine Toxicity: “SAMS”
Posted On August 15, 2021
By Dr.Adel Serag
And has No Comment
1. Lidocaine Toxicity: “SAMS”
Lidocaine is a class IB antiarrhythmic used as a second-line agent and after myocardial infarction.
The therapeutic drug range for is 1.5-5.0 mcg/mL. While generally safe, lidocaine can be toxic if administered inappropriately, and in some cases may cause unintended reactions even when properly administered.
Lidocaine toxicity is seen at levels greater than 5 mcg/mL. Remember the mnemonic SAMS for signs and symptoms of lidocaine toxicity.
- S: Slurred speech
- A: Altered central nervous system
- M: Muscle twitching
- S: Seizures
