{"id":5047,"date":"2014-09-29T23:47:44","date_gmt":"2014-09-29T20:47:44","guid":{"rendered":"http:\/\/seragpsych.com\/wordpress\/?p=5047"},"modified":"2014-11-27T16:47:43","modified_gmt":"2014-11-27T13:47:43","slug":"first-blood-test-for-depression","status":"publish","type":"post","link":"https:\/\/seragpsych.com\/wordpress\/first-blood-test-for-depression\/","title":{"rendered":"First Blood Test for Depression?"},"content":{"rendered":"
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Northwestern University researchers recently identified nine RNA blood markers unique to patients with major depression and developed a blood test they believe could diagnose the disorder in adults.<\/span>\u00a0<\/span><\/p>\n

Their study is published in the September 16 online\u00a0Translational Psychiatry<\/em>.\u00a0<\/span><\/p>\n

Their research involved 64 adults: 32 patients diagnosed with major depressive disorder after a clinical interview, and 32 control subjects without major depressive disorder.<\/p>\n

By analyzing participants\u2019 blood samples, researchers discovered nine RNA blood markers with significantly different levels in patients with depression<\/span><\/strong><\/em><\/span> compared to patients without depression.<\/p>\n

Such markers, researchers said, offer an objective basis for a depression diagnosis.\u00a0<\/span><\/p>\n

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After participants with depression received 18 weeks of cognitive behavioral therapy, their blood was analyzed again. Researchers identified changed levels of specific biomarkers in patients who\u2014according to clinical interviews and self-reported symptoms\u2014benefitted from the intervention<\/span><\/span><\/em><\/strong>.<\/p>\n

Those changes, researchers said, provide the first biological evidence demonstrating the effects of cognitive behavioral therapy.\u00a0<\/span><\/p>\n

Researchers also examined the nine RNA blood markers at baseline of patients who then went on to improve with cognitive behavioral therapy. They found a distinct biomarker pattern, or fingerprint, that was not present in patients who did not improve with cognitive behavioral therapy.\u00a0<\/span><\/p>\n

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References<\/strong><\/p>\n

1.\u00a0Redei EE, Andrus BM, Kwasny MJ, et al. Blood transcriptomic biomarkers in adult primary care patients with major depressive disorder undergoing cognitive behavioral therapy.\u00a0Translational Psychiatry.\u00a0<\/em>2014 Sept. 16. [Epub ahead of print].<\/a><\/p>\n

2.\u00a0First blood test to diagnose depression in adults [press release]. EurekAlert!: Washington, DC; Sept. 16, 2014.<\/a><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Northwestern University researchers recently identified nine RNA blood markers unique to patients with major depression and developed a blood test they believe could diagnose the disorder in adults.\u00a0 Their study is published in the September 16 online\u00a0Translational Psychiatry.\u00a0 Their research involved 64 adults: 32 patients diagnosed with major depressive disorder after a clinical interview, and […]<\/p>\n","protected":false},"author":1,"featured_media":5174,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[427],"tags":[1148,1452,649,1454,1453,1348],"class_list":["post-5047","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-427","tag-biological","tag-blood","tag-depression","tag-markers","tag-rna","tag-testing","entry"],"_links":{"self":[{"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/posts\/5047","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/comments?post=5047"}],"version-history":[{"count":4,"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/posts\/5047\/revisions"}],"predecessor-version":[{"id":5260,"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/posts\/5047\/revisions\/5260"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/media\/5174"}],"wp:attachment":[{"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/media?parent=5047"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/categories?post=5047"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/seragpsych.com\/wordpress\/wp-json\/wp\/v2\/tags?post=5047"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}