Agomelatin = Valdoxan

1 AGOMELATINE THERAPEUTICS Brands • Valdoxan see index for additional brand names Generic? No Class • Neuroscience-based Nomenclature: melatonin multi-modal (Mel-MM) • Agonist at melatonergic 1 and melatonergic 2 receptors • Antagonist at 5HT2C receptors Commonly Prescribed for (bold for FDA approved) • Depression How the Drug Works • Actions at both melatonergic and 5HT2C […]

How to Screen for Sleep Apnea

    To screen for Obstructive Sleep Apnea, we need to check for multiple factors. The STOP-Bang questionnaire looks at these multiple factors. A link to information about the questionnaire is provided below.       1. Snoring Ask the patient and the person who sleeps in the same room. But, many of our patients […]

Psychiatric mnemonics in sleep disorders

    REM: features REM: Rapid pulse/ Respiratory rate Erection Mental activity increase/ Muscle paralysis     Parasomnias:   time of onset SLeep terrors and SLeepwalking occur during SLow-wave sleep (stages 3 & 4). NightmaRE occurs during REM sleep (and is REMembered).       Sleep stages:   features DElta waves during DEepest sleep (stages 3 & 4, slow-wave). dREaM during REMsleep.         Narcolepsy:   symptoms, […]

Psychiatric Mnemonics in Depression

Psychiatry Mnemonics Psychiatry Mnemonics                       Reinforcement schedules: variable ratio SLOT machines show SLOwesTextinction.     Depression: major episode DSM-IV criteria · First, of course depressed mood is one. Then: SIG E CAPS: Sleep disturbance Interest loss Guilt (or intense worthlessness) Energy loss Concentration loss Appetite changes Psychomotor agitation or […]

Best time of the day for best brain power

We fluctuate over the course of a day. Did you know that your brain obeys its own rhythm too? It’s based largely on your human clock, sleep pattern, exposure to light, and genetic makeup — and getting in a groove with its tempo can make you healthier, happier, and have more energy. You can burn […]

Simply to sleep better

10 tips that will make everybody sleep better   It’s estimated that an average 80 year old man sleeps 25 years, just under one third of his life. There is no satisfying answer to why the human organism needs to disconnect from reality during sleep, but one thing’s for sure: it’s one of the most […]

Be calm, even under pressure!

A State of Calmness There’s a lot going on in this world. In fact, there’s probably a lot going on in your life at the moment. So much to do, so little time, and just too much uncertainty. You probably feel as though you are constantly fighting against the odds while trying to make your […]

نومة هنية

· ·   قالت أساطير الرومان القديمة أن اله الليل ( سومنوس) كان له توأمان الأول هو هيبنوس (النوم) و الثاني هو (ثاناتوس ) أو الموت و كانوا يعيشون جميعا في كهف بعيد في أقصى الغرب حيث كانت لا تشرق الشمس هناك أبدا و بجوار هذا الكهف كان يجري نهر النسيان  وكانت تنبت على ضفتيه […]